The Laboratory for High Energy Physics (LPHE) is specialised in particle physics at the École Polytechnique Fédérale de Lausanne (EPFL). The laboratory is part of the Physics Institute (IPHYS) and the School of Basic Sciences (FSB).

The LPHE is engaged in multiple international collaborations. The diversified research activities require the development of techniques in particle detection, and in signal and data processing.

The laboratory is currently participating in the LHCb experiment, whose detector is one of the biggest of the Large Hadron Collider (LHC) at CERN. The analysis of LHCb data allows the LPHE to have a vast research program that is primarily directed towards the study of CP violation and the search of new particles and rare decays.

The laboratory is strongly involved in various teaching activities at EPFL, offering courses in numerous physics topics but also the possibility to follow a master program or an internship directly with researchers.